Area
Dermatology & Cosmetics SafetIndication
Skin sensitizationSystem
In vitroModel references
J Immunotoxicol. 2010 Oct-Dec; 7 (4):255-67;
J Photochem Photo- biol B. 2015 Dec;153:127-36;
Toxicol In Vitro. 2009 Aug;23(5):789-96
Skin sensitization and photosensitivity models. Keratinocites model: NCTC, HaCaT cell lines, IL-18 production
Applications
- Allergenic potential of chemicals.
- Immunotoxicity tests.
- Discrimination between contact vs respiratory aller- gens and/or irritants.
- Molecular markers of skin sensitization.
- 3T3 NRU test.
- UV induced DNA damage.
