Area
Nervous SystemIndication
Trigeminal Neuralgia and Peripheral NeuropathySystem
In vitroModel references
Pain 2018 Jan 159(1): 92-105;
Sci Rep. 2016; 6 35775;
Mol Pain 2011; 7: 30;
J. Neurosci 20 April 2011, 31 (16) 6059- 6066;
Sci Signal. 2019 Jun 18;12(586)
Primary cell culture of sensory neurons, cortical and hippocampal neurons
Applications
- Transient and stable expression of ion channels genes.
- Intracellular calcium effects and other ion fluxes (by imaging and electrophysiological techniques).
- Signaling pathways. Drugs testing.
- Molecular biology: Protein and gene expression techniques (western blot, immunoprecipitation, bio- tinylation, protein expression in yeast).