Area
OpthalmologyIndication
Dry Eye, Keratoconjuctivitis, glaucoma and ocular hypertension, ocular painSystem
In vitroModel references
TM cells:
Sci Rep. 2017 Mar 28;7(1):452;
SC cells:
Prog Retin Eye Res. 2015 Jan;44:86-98;
Exp Eye Res. 2014 Oct; 127:224-35;
Sci Rep. 2019 Apr 1; 9 (1):5392
Ocular cell lines: Trabecular Meshwork (TM) cells and Schlemm’s canal endothelial cells (SC) derived from a human normotensive patient
Applications
- To study cellular aspects of these cells participa- ting and regulating the passage of aqueous humor through the conventional route.
- To decipher molecular mechanisms of Schlemm’s Canal Pore formation and its relationship with glau- coma disease.
- Molecular biology techniques: western blot, calcium free measurement, immunofluorescence (subcellular localization studies), gene expression analysis.
Principal investigators
Xavier Gasull, David Soto, Nuria Comes.Other group publications
X. Gasull at PubMed.
D. Soto at PubMed.
Nuria Comes at PubMed.