Experimental models

Area

Generation of new models

System

Ex vivo
In vivo

New animal models based on the required approach-mouse and rat (rabbit, hamster and guinea pig are also possible).

Expertise

The group CEREMET, with a highly qualified team, offers its knowledge in generating new models in the fields of biochemistry, physiology and metabolism. The services are conducted under the ISO 9001 certification of quality.

Applications

  • Proof of concept.
  • Pharmacokinetics and local tolerance.
  • Pre-clinical studies.
  • Monitoring of blood parameters.
  • Metabolism regulation.
  • Feeding with different diets.
  • Genetic expression.
  • Different routes administration.
  • Surgery procedures.
  • Tissue perfusion (liver, heart and white adipose tissue).
  • Blood and tissue samples obtaining.
  • Development of animal models on request.

Examples

  • Fructose feeding model for hypertriglyceridemia.
  • Diet induced obesity model for obesity and its comorbidities.
  • Hepatic punch model for hepatic regeneration and hemostasis.
  • Hepatectomy model for hepatic regeneration.

Principal investigators

David Ricart.
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