Area
GastrointestinalIndication
Nonalcoholic Steatohepatitis (NASH) and Nonalcoholic Fatty Liver disease (NAFLD)System
Ex vivoModel references
Diabetes. 2016 Oct; 65 (10):3185-99
Mouse derived primary hepatocytes
Applications
- Validation of molecular markers of hepatic disorders and inflammation.
- Screeening of potential therapeutic compounds for liver diseases.
- Fatty Acid Oxidation Assay.
- Oil red O Staining.
- Cell viability studies.
- EMSA.
- Biochemical and biomolecular tests: gene expres- sion (RT-PCR, qPCR), nuclear fractionation, protein expression and protein phosphorylation (WB).
