Area
Ear and Mastoid ProcessIndication
Other disorders of the ear: Presbycusis (Age-Related Hearing Loss)System
In vivoModel references
Elife. 2018 Jan 22;7. pii: e31511
Model of age-related hearing loss in C57BL6/J-129Sv mice: Slc7a8 -/- KO, Slc7a8 +/-
Applications
- Molecular basis of ARHL.
- Disease development and stages.
- Phenotypic studies of auditory system.
- Cytoarchitecture of inner ear.
- Cell type specific biomarkers study.
- Syte-directed mutagenesis studies.
- Molecular biology techniques from animal tissue: WB, PCR, cellular localization studies.
- High throughput techniques (omic studies, proteo- mics, transcriptomics) from mouse tissue.