Area
CardiovascularIndication
CardiomyopathySystem
In vivoModel references
under development
Mice models of Endoplasmatic Reticulum Stress: Male ATF3 -/- and ATF3+/+ mice and male GADD45a -/- and ATF3 +/+ mice model
Applications
- Validation of molecular markers of cardiac disorders.
- Test of therapeutic cardiomyopaties candidates.
- Biochemical and biomolecular tests: gene expression (RT-PCR, qPCR), nuclear fractionation, protein expression and protein phosphorylation (WB).
- Cell viability studies.
- EMSA.
