Area
GastrointestinalIndication
Nonalcoholic Steatohepatitis (NASH) and Nonalcoholic Fatty Liver disease (NAFLD)System
In vitroModel references
Biochim Biophys Acta. 2015 May;1852(5):1049-58
Human derived hepatocellular carcinoma cell lines: HepG2, Huh7.
Applications
- Validation of molecular markers of hepatic disorders and inflammation.
- Screeening of potential therapeutic compounds for liver diseases.
- Fatty Acid Oxidation Assay.
- Oil red O Staining.
- Cell viability studies.
- EMSA.
- Biochemical and biomolecular tests: gene expression (RT-PCR, qPCR), nuclear fractionation, protein expression and protein phosphorylation (WB).