Area
Endocrine, Nutritional and Metabolic DiseasesIndication
CystinuriaSystem
In vivoModel references
J Am Soc Nephrol. 2018 Jun; 29 (6):1624-1635
Double KO LAT2-TAT1 mice: DKO Slc7a8/Slc3a2 model
Applications
- Aminoaciduria studies.
- Renal transporters study.
- Molecular basis of renal reabsorption on different experimental diets.
- Phenotypic studies.
- Urinary bladder calculi quantification by X- ray analysis.
- Metabolites studies from urine and blood.
- Molecular Biology techniques from animal tissue: WB, PCR, IP, IC.
- High throughput techniques (omic studies, proteo- mics, transcriptomics) from mouse tissue.
- Test of drug candidates.