Area
Nervous SystemIndication
LeukodystrophiesSystem
In vivoModel references
Human Molecular Genetics, 2017, Vol. 26, No.13;
Nat Commun, 2014 Mar 19; (5):3475
Clc2/Glial CAM -/- mouse model
Applications
- Channel studies.
- Phenotypic studies.
- Molecular biology techniques from animal tissue.
- High throughput techniques.
- Test of drug candidates.
Principal investigators
Raul Estevez Povedano, Virginia Nunes.Other group publications
Model relevance
Recapitulates phenotypic features of Leukodystrophy, CLCN2-related leukoencephalopathy (CC2L) and Mega- lencephalic leukoencephalopathy.
