Area
Nervous SystemIndication
EpilepsySystem
In vivoModel references
Mol Neurobiol. 2018 May; 55(5):4437-4452;
Neu- ropharmacology. 2018 Mar 15;131:440-452;
Front Biosci. 2017 Jan 1;22:795-814;
J Neurochem. 2010 Sep 1;114(5):1315-22
Chemically-induced epilepsy rodent model: Kainic Acid (KA) administration mainly induces neuronal loss in the hippocampus
Applications
- KO mice models.
- Epilepsy disease molecular.
- Mechanisms and physiologic studies.
- Evaluation of epilepsy inductors and neuroprotectant drugs.
- Seizure-related behavioural studies.
- Biomolecular experimentation: cytotoxicity tests, inflammation tests, immunolocalization, ELISA.
