Area
OncologyIndication
Malignant CachexiaSystem
In vivoModel references
J Cachexia Sarcopenia Muscle. 2015 Mar; 6 (1):84- 94;
Oncotarget. 2015 Dec 22; 6 (41):43202-15
C26 colon adenocarcinoma: model of cancer cachexia in mice of the Balb strain
Applications
- Normal vs pathologic studies.
- Therapies effectiveness of cancer cachexia.
- Discovery and validation of targets and pathways involved in the pathology and syndrome evolution.
- Molecular disease markers validation.
- Molecular biology techniques: WB, RT-PCR, optical and electron microscopy, IB, TUNEL.
- Tumor weight measurement.
- Strength measurement (Grip strength test).
- Locomotor activity measurement (IR actimeter System with ACTITRAK software).
- Tapes to train animals. Blood tests.
Principal investigators
Josep Maria Argilés, Silvia Busquets, Francisco López-Soriano.Other group publications
F. López-Soriano at PubMed.
S. Busquets at PubMed.
JM. Argilés at PubMed.
