Area
Nervous SystemIndication
Trigeminal Neuralgia and Peripheral NeuropathySystem
In vitroModel references
Sci Signal. 2019 Jun 18; 12 (586);
J Physiol. 2017 Nov 15;595(22):6993-7008;
Front Mol Neurosci. 2018 Aug 8;11:275
Stablished cell lines (Hippocampus, cerebral cortex)
Applications
- Transient and stable expression of ion channels genes.
- Intracellular calcium effects and other ion fluxes (by imaging and electrophysiological techniques).
- Signaling pathways.
- Drugs testing.
- Molecular biology: Protein and gene expression techniques (western blot, immunoprecipitation, bio- tinylation, protein expression in yeast).