IndicationOther interstitial pulmonary diseases with fibrosis
Mol Biol Cell. 2017 Dec 15; 28 (26): 3741–3755
Primary fibroblasts (normal/ pathologic) cultures from human tissue explants: cell lines culture of mesenchymal/epithelial origin.
- Normal vs pathologic studies.
- Mechanisms of drug action.
- Potential targets identification.
- Therapeutic effects validation.
- Drug combinations and reproval from preexisting treatments.
- Drug resistance mechanisms.