Area
Nervous SystemIndication
Trigeminal Neuralgia and Peripheral NeuropathySystem
In vitroIn vivo
Model references
Pain. 2016 Feb; 157 (2): 399–417;
Mol Pain. 2011; 7: 30
Neuronal excitability models. Imaging techniques: intracellular calcium imaging and live-cell functionality imaging with fluorescent dyes
Applications
- Direct measurement of the calcium fluxes within neurons.
- Study of roles of calcium ions in different physiologi- cal and pathological situations.
- Intracellular signaling that control pain pathways.
- Sensory neurons response to drugs compounds and gene modifications cell volume, nitric oxide.