Area
Nervous SystemIndication
Muscular DystrophySystem
In vitroModel references
Muscle Nerve. 2018 Feb 9;
Hum Mutat. 2016 Jan;37(1):74-83
Model of Xenopus oocytes expressing and/or coexpressing CLCN1 and VRAC (wt and mutations) and CLC1 chloride channel proteins
Applications
- Channel osmosensitivity.
- Functional expression, modification and characte- rization of voltage channels, related subunits and regulatory proteins.
- Voltage channel activators and inhibitors analysis.
- 3D studies of voltage channels structure, binging molecules and mechanisms.
