Experimental models

Area

Immunology / Autoimmune

Indication

Programming and development of the immune system

System

In vivo

Model references

Developmen- tal and Comparative Immunology 2007; 31 (12), pp, 1264-1277;
Pediatric Research 2005; 58 (5), pp. 885- 891;
Pediatric Research 2005; 58 (1), pp. 164-169

Immune development during gestation and sucking period

Applications

  • Testing the effect of bioactive compounds.
  • Diets design and ingredient incorporation into feed.
  • Host immune development: humoral and cellular immune response, composition of lymphoid tissues.
  • Intestinal immune system: microbiota composition, intestinal barrier.
  • Immune functions: phagocytosis, cytotoxic activity, lymphocyte composition and functionality.

Principal investigators

Àngels Franch, Francisco J. Pérez-Cano, Margarida Castell, M. José Rodríguez-Lagunas, Malén Massot-Cladera.

Other group publications

PubMed publications.

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