Area
Endocrine, Nutritional and Metabolic DiseasesIndication
Type 2 Diabetes MellitusSystem
In vivoHigh fat diet induced ER stress model (under development).
Male ATF3-/- mice and wildtype littermates (ATF3+/+).
GADD45a -/- mice and wildtype littermates (GAD- D45a +/+).
Applications
- Fatty acids, glucose and specific markers measu- rement in serum and tissues (white adipose tissue, blood, hepatocytes).
- Glucose Tolerance Test (GTT).
- Insulin Tolerance Test (ITT).
- Piruvate Tolerance Test (PTT).
- Biochemical and biomolecular techniques.
- EMSA: transcription factors assessment.
