Area
Dermatology & Cosmetics SafetIndication
In vivo models: HET-CAM eggsSystem
In vivoModel references
Toxicol In Vitro. 2006 Sep;20(6):1066-70;
Food Chem Toxicol. 2004 Aug;42 (8):1287-90
HET-CAM fertilized chicken eggs: before the 10th day which is when the embrio develops the nervous system
Applications
- Alternative eye and mucoses irritation testing: The chorioallantoic membrane is used to simulate the effect of cosmetics at ocular level.
Model advantages
This system can also be used to evaluate anti-tumor treatments or angiogenesis studies.
