Area
Ear and Mastoid ProcessIndication
Diseases of the Inner Ear: Disorders of vestibular function, vertiginous syndromesSystem
In vivoModel references
Arch Toxicol. 2019 Feb;93 (2):417-434;
J Assoc.Res Otolaryngol. 2019 Jul 11;
Neurotoxicology. 2018 Jul; 67:270-278
Animal models of sensory neurotoxicity auditory, visual, olfactory, dorsal root ganglia (mouse, rat)
Applications
- Neurotoxicity assessment.
- Regeneration studies.
- Behavioral evaluation of auditive and vestibular dysfunction.
- Drugs and chemicals testing.
- Histopathologic analysis of vestibular system: identification of molecular targets in the vestibular periphery.
- Vestibular toxicology and pharmacology.
- Histology and gene expression studies of the sen- sory epithelia of the inner ear: RT-PCR, RNA-seq, inmuno-histochemistry and confocal microscopy, scanning electron microscopy, transmission electron microscopy, light microscopy in semi-thin sections.
