IndicationDry Eye, Keratoconjuctivitis, glaucoma and ocular hypertension, ocular pain
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Animal models (mouse, rat and rabbit) of ocular pain by applying painful or pruritic substances in the ocular surface
- To study ocular pain after inflammation, injury or dry eye diseases.
- Topical application of substances to decipher neural mechanisms regulating intraocular pressure and ion K+ and Cl– channels that regulate contraction, shape and cell volume in trabecular cells that control aqueous humor flow and intraocular pressure in the eye.
- Understand the sensory ocular pathophysiology.
Ocular pain tests
- Blinking test.
- Thermal / mechanical sensitivity.
- Lacrimation (tear secretion measurement).