Experimental models

Area

Allergy

Indication

Allergy, unspecified

System

In vivo

Model references

Experimental Biology and Medicine 2015; 240 (10), pp. 1373-1377;
PLoS ONE 2015; 10 (4), art. no. 0125314;
Clinical Immunology, Endocrine and Metabolic Drugs 2014; 1 (2), pp. 89- 101

Allergy models (systemic, food, respiratory) in rats.

Applications

  • Screening of new drugs.
  • Testing the effect of bioactive compounds.
  • Diets design and ingredient incorporation into feed.
  • Biomarkers: disease severity and duration.
  • Host immune response evaluation: IgE and other specific antibodies, anaphylactic shock.
  • Role of the microbiota.

Principal investigators

Margarida Castell, Francisco J. Pérez-Cano, Àngels Franch, M. José Rodríguez-Lagunas, Malén Massot-Cladera.

Other group publications

PubMed publications.

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