Area
CardiovascularIndication
CardiomyopathySystem
In vitroModel references
Int J Cardiol. 2014 Jun 1; 174(1):110-8;
Dis Model Mech. 2015 Sep;8(9):1081-91
Human cardiac AC16 cell line: Fusion of primary ventricular cells with SV-40 transformed fibroblasts (not transferable cell line)
Applications
- Deciphering molecular markers of cardiac disorders.
- Test of therapeutic candidates.
- Gene transfection.
- Biochemical and biomolecular tests from cells and supernatants: gene expression (RT-PCR, qPCR), nuclear fractionation, protein expression and protein phosphorylation (WB), enzyme activity.
- Cell viability studies.