Area
OncologyIndication
Malignant CachexiaSystem
In vivoModel references
Biochimie. 2018 Jun; 149:79-91;
Oncotarget. 2015 Dec 22; 6 (41):43202-15
Ascites hepatoma Yoshida AH-130: model of cancer cachexia in rats of the Wistar strain
Applications
- Normal vs pathologic studies.
- Therapies effectiveness of cancer cachexia.
- Discovery and validation of targets and pathways involved in the pathology and syndrome evolution.
- Molecular disease markers validation.
- Molecular biology techniques: WB, RT-PCR, optical and electron microscopy, IB, TUNEL.
- Tumor weight measurement.
- Strength measurement (Grip strength test).
- Locomotor activity measurement (IR actimeter Sys- tem with ACTITRAK software).
- Tapes to train animals. Blood tests.
Principal investigators
Josep Maria Argilés, Silvia Busquets, Francisco López-Soriano.Other group publications
F. López-Soriano at PubMed.
S. Busquets at PubMed.
JM. Argilés at PubMed.