{"id":1801,"date":"2017-09-22T12:32:47","date_gmt":"2017-09-22T11:32:47","guid":{"rendered":"http:\/\/161.116.26.48\/que-hacemos\/tecnologias-materiales-y-licencias\/tecnologias-para-licenciar\/cachexia-score-casco\/"},"modified":"2017-11-07T11:09:22","modified_gmt":"2017-11-07T10:09:22","slug":"cachexia-score-casco","status":"publish","type":"page","link":"https:\/\/www.fbg.ub.edu\/es\/que-hacemos\/tecnologias-materiales-y-licencias\/tecnologias-para-licenciar\/cachexia-score-casco\/","title":{"rendered":"Scoring CACHEXIA: CASC-IN, CASCO &#038; miniCASCO"},"content":{"rendered":"<h3>Introduction<\/h3>\n<p>Cachexia is a term originating from the Greek \u201ckakos\u201d and \u201chexis\u201d meaning \u201cbad condition\u201d. The cachectic state is observed in many pathological conditions such as cancer, COPD, sepsis or chronic heart failure<sup>1<\/sup>.<br \/>\nDespite the efforts to find suitable clinical biomarkers to map out the different cohorts affected by cachexia, some type of cachexia scoring tool is still necessary to classify patients according to the severity of the syndrome and take decisions about their treatment and support measures.<br \/>\nBearing this in mind, the object of the present technological tools is to fulfil the existing gap in the classification of cachectic patients by introducing a new score that takes into consideration the main parameters involved in the cachectic syndrome.<\/p>\n<h3>Description. How it works?<\/h3>\n<p>The invention consists of three different questionnaires: CASC-IN, CASCO and miniCASCO. CASC-IN allows deciding whether the patient suffers from cachexia or not. CASCO classifies cachectic patients depending on cachexia severity. Additionally, a simplified version of CASCO questionnaire (miniCASCO) has been developed in order to permit faster performance. Both CASCO and miniCASCO use a score scale going from 0 to 100 and take into account five main different factors to evaluate the patient status: <em>body weight<\/em> <em>loss and composition<\/em>; <em>Inflammation, metabolic disturbances and Immunosuppression<\/em>; <em>physical performance; anorexia<\/em> and <em>quality of life<\/em><sup>2<\/sup>. Our recent study provides clinical validation for the use of the score<sup>3<\/sup>. Three different groups of cachectic cancer patients were established according CASCO validation: mild cachexia (15 \u2264 x \u2264\u00a0 28), moderate cachexia (29\u2264 x \u2264\u00a0 46), and severe cachexia (47 \u2264 x \u2264\u00a0 100).<\/p>\n<h3>Field of Uses<\/h3>\n<p>CASCO can be used in patients with cancer (other diseases such as AIDS, sepsis, severe burn, chronic obstructive pulmonary disease, cardiovascular pathology, nutrition disorder, neuromuscular disease, hyperthyroidism, muscle atrophy and\/or dystrophy are under development).<\/p>\n<h3>Current stage of development<\/h3>\n<p>CASCO (english version)<br \/>\nminiCASCO (english version)<br \/>\nCASC-IN (english version)<\/p>\n<h3>Intellectual Property rights<\/h3>\n<p>Copyright\u00ae Universitat de Barcelona.<br \/>\nAll rights reserved.<\/p>\n<h3>Access<\/h3>\n<p>CASC-IN, CASCO and miniCASCO are available online:<br \/>\n<a href=\"https:\/\/www.ub.edu\/cancerresearchgroup\/index.php\">https:\/\/www.ub.edu\/cancerresearchgroup\/index.php<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Introduction Cachexia is a term originating from the Greek \u201ckakos\u201d and \u201chexis\u201d meaning \u201cbad condition\u201d. The cachectic state is observed&#8230;<\/p>\n","protected":false},"author":1,"featured_media":1802,"parent":1399,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-tecnologies.php","meta":{"_acf_changed":false,"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-1801","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages\/1801","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/comments?post=1801"}],"version-history":[{"count":3,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages\/1801\/revisions"}],"predecessor-version":[{"id":3039,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages\/1801\/revisions\/3039"}],"up":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages\/1399"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/media\/1802"}],"wp:attachment":[{"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/media?parent=1801"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}