In the last decades, limitations of the 2D cell models and ethical issues\u00a0on the use of animal models have evidenced the need for relevant in vitro models to test drug efficacy on preclinical stages. 3D cell culture models are considered the next-generation in vitro models to study diseases in a physiologically relevant manner and better predict drug efficacy. Human tissues are not flat. The topography, curvature and mechanical properties of tissues define their behavior. Still, most in vitro cell assays are performed in plastic\u00a0cell culture.<\/p>\n
Thus,\u00a03D scaffolds mimicking\u00a0the\u00a0architecture and mechanical properties of human tissues are yet an unmet market need. Cell-based models of the intestinal tissue are crucial to drive research progress in drug development and disease modelling. <\/b>High impact\/high prevalence fields such as oral drug uptake and metabolism, compound\u00a0toxicity assays, nutrition protocols, intestinal infections, inflammatory diseases, or cancer rely on the predictive capabilities of intestinal in vitro assays and are willing to absorb efficient solutions that better resemble\u00a0our bodies, in a cost-effective way.<\/p>\nMarket<\/h3>\n
The global digestive health products market size was valued at USD 44.4 billion in 2022<\/b> and is expected to expand at a compound annual growth rate (CAGR) of 8.2% from 2022 to 2030. Global inflammatory bowel disease treatment market size was valued at USD 20.33 billion in 2022<\/b> and is expected to expand at a (CAGR) of 3.6% from 2023 to 2030.\u00a0Complementarily, global 3D bioprinting market size was valued at USD 1.7 billion in 2021<\/b> and is expected to expand at a (CAGR) of 15.8% from 2022 to 2030.<\/p>\n
In western countries, gut health is gaining popularity among consumers, supporting the awareness of a healthy gut microbiome. Accurate models and platforms to test the effect of products on the status of gut microbiome<\/b> will become a challenge and a great market opportunity<\/b> for companies adding this capabilities to their portfolios.<\/p>\nAsset<\/h3>\n
GUT3D-PLATE is a ready-to-use cell culture substrate <\/b>that\u00a0reproduce the small intestinal architecture<\/b> for\u00a03D cell culture assays. The hydrogel structure mimics\u00a0 of the intestinal tissue. Our hydrogel-based\u00a03D bioprinting approach<\/b> allows quick and reliable fabrication of substrates with relevant geometrical, mechanical and physicochemical properties.<\/p>\n
GUT3D-PLATE\u00a0wants to fulfil the market need of\u00a0low-cost and easy-to-use cell substrates<\/b>\u00a0that would speed-up the early-phases of drug\u00a0discovery, improve disease modelling and reduce the use of animals in\u00a0research.<\/p>\n Challenge In the last decades, limitations of the 2D cell models and ethical issues\u00a0on the use of animal models have…<\/p>\n","protected":false},"author":2,"featured_media":17117,"parent":1395,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-tecnologies.php","meta":{"_acf_changed":false,"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-17153","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages\/17153","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/comments?post=17153"}],"version-history":[{"count":3,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages\/17153\/revisions"}],"predecessor-version":[{"id":17196,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages\/17153\/revisions\/17196"}],"up":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/pages\/1395"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/media\/17117"}],"wp:attachment":[{"href":"https:\/\/www.fbg.ub.edu\/es\/wp-json\/wp\/v2\/media?parent=17153"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Current stage of development<\/strong><\/h3>\n
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