{"id":12038,"date":"2021-04-13T12:00:01","date_gmt":"2021-04-13T10:00:01","guid":{"rendered":"http:\/\/161.116.26.48\/?p=12038"},"modified":"2021-04-13T12:00:01","modified_gmt":"2021-04-13T10:00:01","slug":"new-international-consortium-to-promote-stem-cell-based-therapy-for-huntingtons-disease","status":"publish","type":"post","link":"https:\/\/www.fbg.ub.edu\/en\/news\/new-international-consortium-to-promote-stem-cell-based-therapy-for-huntingtons-disease\/","title":{"rendered":"A new international consortium to promote Stem Cell-Based Therapy for Huntington&#8217;s disease"},"content":{"rendered":"<p style=\"font-weight: 400;\">The Stem Cells for Huntington&#8217;s Disease (<a href=\"https:\/\/www.sc4hd.org\/\">SC4HD<\/a>) is a new international consortium created to promote\u00a0advanced therapy medicinal product (ATMP) through cell transplantation studies on Huntington\u2019s Disease. The entity, made up of twenty-eight renowned researchers from ten countries, has been officially presented in a recent publication in the<em>\u00a0J<\/em><em>ournal of Huntington\u2019s Disease<\/em>.<\/p>\n<p style=\"font-weight: 400;\">The main goals of SC4HD researchers are to work together with the HD community, develop criteria and guidance and address the main challenges to rapidly and safely bring potentially beneficial stem cell-based therapies to patients with this devastating disease.<\/p>\n<p style=\"font-weight: 400;\">According to Josep M. Canals, director of Creatio and member of the steering committee of SC4HD, \u201cthere is an exciting opportunity to apply stem cell-based therapies in Huntington\u2019s disease (HD), a devastating neurodegenerative disease that mainly affects neurons in the brain nucleus known as striatum\u201d.\u00a0 Josep M. Canals is a tenured university lecturer at the Department of Biomedical Sciences of the Faculty of Medicine and Health Sciences of the UB, and director of the Production and Validation Center for Advanced Therapies (<a href=\"https:\/\/www.ub.edu\/creatio\/#!\/home\">Creatio)<\/a>, a TECNIO center for the production of Advanced Therapy Medicinal Products (ATMPs) in Catalonia. Also, he leads the Stem Cell and Regenerative research group of the UB.<\/p>\n<p style=\"font-weight: 400;\">To date, most experimental cell therapies\u00a0 have focused on the striatum aiming to replace the lost striatal neurons during the disease process. Therefore, this aims to repair the neuronal circuit and increase the survival of the remaining neuronal and glial striatal cells. Technological advances aimed to direct the differentiation of stem cells to desired neural types have opened new strategies for restoring damaged neuronal circuits in Huntington&#8217;s.<\/p>\n<p style=\"font-weight: 400;\">The SC4H consortium brings together experts in stem cell biology, cell transplantation, clinical grade cell production, neurosurgery, and clinical evaluation. Its aim is to accelerate the safe clinical translation of stem cell therapy and to provide a comprehensive standardization and guidance for the field, spanning the full range of therapeutic considerations.<\/p>\n<p style=\"font-weight: 400;\"><a href=\"https:\/\/www.ub.edu\/web\/ub\/en\/menu_eines\/noticies\/2021\/03\/020.html?\" target=\"_blank\" rel=\"noopener\">More information<\/a><\/p>\n<p><iframe loading=\"lazy\" title=\"4258 SC4HD eng\" width=\"770\" height=\"433\" src=\"https:\/\/www.youtube.com\/embed\/8Pb0nkKnXWE?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Stem Cells for Huntington&#8217;s Disease (SC4HD) is a new international consortium created to promote\u00a0advanced therapy medicinal product (ATMP) through&#8230;<\/p>\n","protected":false},"author":2,"featured_media":12032,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-12038","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/posts\/12038","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/comments?post=12038"}],"version-history":[{"count":1,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/posts\/12038\/revisions"}],"predecessor-version":[{"id":12039,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/posts\/12038\/revisions\/12039"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/media\/12032"}],"wp:attachment":[{"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/media?parent=12038"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/categories?post=12038"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/tags?post=12038"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}