{"id":10865,"date":"2020-11-02T10:08:38","date_gmt":"2020-11-02T08:08:38","guid":{"rendered":"http:\/\/161.116.26.48\/?p=10865"},"modified":"2020-11-02T10:08:38","modified_gmt":"2020-11-02T08:08:38","slug":"creatio-and-datascience-collaborate-to-develop-an-in-silico-model-for-drug-screening-in-neurodegenerative-diseases","status":"publish","type":"post","link":"https:\/\/www.fbg.ub.edu\/en\/news\/creatio-and-datascience-collaborate-to-develop-an-in-silico-model-for-drug-screening-in-neurodegenerative-diseases\/","title":{"rendered":"Creatio and DataScience collaborate to develop an in silico model for drug screening in neurodegenerative diseases"},"content":{"rendered":"<p>The Research Group on Stem Cells and Regenerative Medicine and the Research Group on Computer Vision and Machine Learning of the University of Barcelona have established a strategic partnership with the aim of studying the development of areas of the brain damaged by neurodegenerative diseases through deep learning technologies.<\/p>\n<p>The joint development of an <em>in silico<\/em> model allows to make simulations, to create mathematical models, and to visualize medical and biological processes, which in turn enables accurate predictions and simulations of real biological processes in a virtual environment, thus anticipating possible patient reactions to a drug.<\/p>\n<p>On the basis of a high-performance analysis of human pluripotent stem cell differentiation, this model, aimed at replicating neurodegenerative Huntington&#8217;s disease, will allow to carry out pharmacological <em>in silico<\/em> screening studies for this devastating disease, which currently has no effective treatment.<\/p>\n<p>The collaboration between <a href=\"https:\/\/www.ub.edu\/creatio\/#!\/home\" target=\"_blank\" rel=\"noopener\">Creatio<\/a> and <a href=\"http:\/\/datascience.barcelona\/\" target=\"_blank\" rel=\"noopener\">DataScience@UB<\/a> is a clear example of the evolution of medical experimentation. The advances in artificial intelligence in the field of biological data have resulted in <em>in silico<\/em> models as an option for the future, due to their potential to accelerate drug development processes. Furthermore, this collaboration will further progress in innovative techniques, leading to cross-cutting knowledge that will facilitate the development of treatments to combat the complexity of neurodegenerative diseases currently affecting society.<\/p>\n<p>These two groups are recognized as quality research groups by AGAUR (2017 SGR 1408; 2017 SGR 1742), and are part of the Creatio and DataScience@UB centres, respectively, both of which hold the TECNIO certification granted by Acci\u00f3 for developing the most innovative technologies in the Catalan R&amp;D&amp;i system, providing differential technological capacities, and transferring them to companies. The project is partially funded by the CHDI Foundation for the cure of Huntington&#8217;s disease, which has entrusted research projects to Creatio since 2012.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Research Group on Stem Cells and Regenerative Medicine and the Research Group on Computer Vision and Machine Learning of&#8230;<\/p>\n","protected":false},"author":2,"featured_media":10860,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-10865","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/posts\/10865","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/comments?post=10865"}],"version-history":[{"count":1,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/posts\/10865\/revisions"}],"predecessor-version":[{"id":10866,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/posts\/10865\/revisions\/10866"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/media\/10860"}],"wp:attachment":[{"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/media?parent=10865"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/categories?post=10865"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fbg.ub.edu\/en\/wp-json\/wp\/v2\/tags?post=10865"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}